After experimenting on himself and becoming invisible, scientist Jack Griffin, now aggressive due to the drug’s effects, seeks a way to reverse the experiment at any cost.

When an archaeologist uncovers a strange skull in a foreign land, the residents of a nearby town begin to disappear, leading to further inexplicable occurrences.

When renowned crime novelist Harlan Thrombey is found dead at his estate just after his 85th birthday, the inquisitive and debonair Detective Benoit Blanc is mysteriously enlisted to investigate. From Harlan’s dysfunctional family to his devoted staff, Blanc sifts through a web of red herrings and self-serving lies to uncover the truth behind Harlan’s untimely death.